Evosphere monodisperse HPLC particles

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HALO PCS: 3 for 2

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ISSS 2024 (Messina, Italy)

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Excellent chiral columns from the Lion City

ChiralCE and ChiralCD CSPs separate 80% of chiral compounds

ChiralTek manufactures six series of chemically-bonded chiral columns for HPLC, SFC, and UPLC:
Amylose-bonded ChiralAM columns
Cyclodextrin-bonded ChiralCD columns
Cellulose-bonded ChiralCE columns
Amylose-appended cyclodextrin-bonded ChiralAMCD columns
Amylose-appended cellulose-bonded ChiralAMCE columns, and
Cellulose-appended cyclodextrin-bonded ChiralCECD columns. The ChiralAMCD, ChiralAMCE, and ChrialCECD columns are novel columns containing unique complex chiral selectors which are firstly created and manufactured by ChiralTek.

ChiralTek CSPs

Phase Functional group Particle, um
ChiralAM-1 Phenylcarbamate-Amylose bonded phase 3
ChiralAM-2 3,5-Dimethylphenylcarbamate-Amylose bonded phase 3
ChiralAM-3 3-Chloro-4-methylphenylcarbamate-Amylose bonded phase 3
ChiralAM-5 3-Chloro-5-methyl-phenylcarbamate-Amylose bonded phase 3
ChiralAMCD-1 Phenylcarbamate-Amylose-appended-beta-Cyclodextrin bonded phase 3
ChiralAMCD-2 3,5-Dimethylphenylcarbamate-Amylose-appended-beta-Cyclodextrin bonded phase 3
ChiralAMCD-3 3-Chloro-4-methylphenylcarbamate-Amylose-appended-beta-Cyclodextrin bonded phase 3
ChiralAMCE-1 Phenylcarbamate-Amylose-appended-Cellulose bonded phase 3
ChiralAMCE-2 3,5-Dimethylphenylcarbamate-Amylose-appended-Cellulose bonded phase 3, 5, 10
ChiralAMCE-3 3-Chloro-4-methylphenylcarbamate-Amylose-appended-Cellulose bonded phase 3
ChiralAMCE-5 3-Chloro-5-methyl-phenylcarbamate-Amylose-appended Cellulose-bonded phase 3
ChiralCE-1 Phenylcarbamate-Cellulose bonded phase 2, 3, 5, 10
ChiralCE-2 3,5-Dimethylphenylcarbamate-Cellulose bonded phase 2, 3, 5, 10
ChiralCE-3 3-Chloro-4-methyl-phenylcarbamate-Cellulose bonded phase 3
ChiralCD-1 beta-Cyclodextrin-1 bonded phase 2, 3
ChiralCD-2 beta-Cyclodextrin-2 bonded phase 3
ChiralCD-3 gamma-Cyclodextrin-3 bonded phase 3
ChiralCD-4 alpha-Cyclodextrin-4 bonded phase 3
ChiralCD-5 beta-Cyclodextrin-5 bonded phase 3
ChiralCD-6 beta-Cyclodextrin-6 bonded phase 3
ChiralCECD-1 Phenylcarbamate-Cellulose-appended-beta-Cyclodextrin bonded phase 2, 3, 5, 10
ChiralCECD-2 3,5-Dimethylphenylcarbamate-Cellulose-appended-beta-Cyclodextrin bonded 3, 5, 10
ChiralCECD-3 3-Chloro-4-methyl-phenylcarbamate-Cellulose-appended-beta-Cyclodextrin bonded 3


ChiralTek columns are ideal alternatives for other supplier’s products as follows -
ChiralTek ChiralCE-1, ChiralAMCE-1, and ChiralCECD-1 columns are ideal alternatives for Daicel Chiralcel OC columns.
ChiralTek ChiralCE-2, ChiralAMCE-2 and ChiralCECD-2 columns are ideal alternatives for Phenomenex Lux Cellulose-1 and Daicel Chiralcel OD, OD-H, OD-3, OD-RH, OD-3R, and Chiralpak IB columns.
ChiralTek ChiralAM-2, ChiralAMCE-2 and ChiralAMCD-2 columns are ideal alternative columns for Daicel Chiralpak IA, AD, and AD-H columns.
Chiraltek ChiralCE-3, ChiralAMCE-3 and ChiralCECD-3 columns are ideal alternatives for Phenomenex Lux Cellulose-2 column and Daicel Chiralcel OZ, OZ-H, OZ-3, OZ-RH, OZ-3Rcolumns.
ChiralTek ChiralAMCE-4 columns are ideal alternatives for Daicel Chiralpak IC columns.
ChiralTek ChiralAMCE-5 columns are ideal alternatives for Daicel Chiralpak IG columns.
ChiralTek ChiralCD-1, ChiralCD-2, ChiralCD-5, ChiralCD-6, ChiralAMCD-1, ChiralAMCD-2,ChiralCECD-1, ChiralCECD-2 columns are ideal alternative columns for Merck ChiralDex columns.
ChiralTek ChiralCD-3 columns are ideal alternatives for Sigma Astec Cyclobond II and II AC columns.
ChiralTek ChiralCD-5 columns are ideal alternative columns for Sigma Astec Cyclobond I 2000 DMPand Cyclobond I 2000 DNP columns.


ChiralTek chiral HPLC columns


Screening Kit-1  (three columns, 150x2mmx3um)
Chiral Separation Screening Kit-1 contains 813-CE1-03 (ChiralCE-1), 823-CD1-03 (ChiralCD-1), and 823-CD4-03 (ChiralCD-4) columns.

Screening Kit-2  (six columns, 150x2mmx3um)
Chiral Separation Screening Kit-2 contains 813-CE1-03 (ChiralCE-1), 813-CE2-03 (ChiralCE-2), 823-CD1-03 (ChiralCD-1), 823-CD2-03 (ChiralCD-2), 823-CD3-03 (ChiralCD-3),and 823-CD4-03 (ChiralCD-4) columns.


Column protection

The ChiralCE and ChiralCD columns are shipped in a mixture of methanol/isopropanol. For use under reversed-phase conditions, the columns should be flushed with methanol following by mobile phase until reaching a constant column pressure. Similarly, for use under normal-phase conditions, the columns need to be flushed with isopropanol following by mobile phase until achieving a stable baseline signal.
A standard C18 guard cartridge can be used for reversed-phase conditions and a DIOL guard cartridge for normal-phase conditions to protect the analytical columns.

M05CLDSK (Kromasil C18 Guard Starter Kit, cartridges 5/pk. + Holder + Coupler)
S05DIDSK (Kromasil DIOL Guard Starter Kit, cartridges 5/pk. + Holder + Coupler)

Guard cartridge system GUARD CARTRIDGE SYSTEM
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ChiralTek SPE products

ChiralTek HLE SPE
The Hydrophilic and Lipophilic Extraction (HLE) sorbent was prepared through a specially-designed procedure by bonding multiple chemical function groups, including DIOL, C18 (ODS), vinylpyrrolidone and divinylbenzene (HLB) onto a special type of porous composite material. The HLE cartridges can be used as direct replacement of Waters HLB cartridges due to functioning of vinylpyrrolidone and divinylbenzene groups in the HLE particles.

ChiralTek UPE SPE
The Ultra-high Performance Extraction (UPE) sorbents were prepared through a specially-designed procedure by bonding C18 (ODS) and ChiralTek proprietary functional groups onto high-quality porous spherical silica particles. Compared to traditional SPE cartridges, the UPE cartridges contain much thinner column beds and much smaller volume of the packing materials (only 5 to 10% of other SPE cartridges). After loading the sample, extremely small amount of organic solvents (0.2-0.3mL for UPE-20 and UPE-30; 1.2-1.5mL for UPE-60 and UPE90 cartridges) can be used to quickly elute and simultaneously concentrate the extracts in the UPE cartridges.

ChiralTek PSPE Systems
The PSPE series of positive-pressure solid phase extraction (SPE) systems are successfully manufactured by ChiralTek using a novel flow-path-integration technique. They are designed for complicated biological and environmental samples. The PSPE systems are controlled by built-in single-chip microcomputer units (SCU) and driven by compact air-pumps with easy operations. They are the first type of compact, affordable, and cost-efficient commercial positive-pressure SPE systems which can completely eliminate cross-over contaminations.